Hesperidin is a flavonoid you get from citrus fruits, especially oranges and lemons. Supplement makers extract and concentrate it for its antioxidant abilities.
People take it to keep blood vessels and capillaries strong and to support healthy circulation. Many also include it in an antioxidant stack for immune function and skin resilience.
A daily dose of 500 to 1000 mg is common. Taking it with food helps your body absorb it better. You will often see it combined with diosmin and other citrus bioflavonoids for broader vascular support.
Side effects are uncommon. Some people notice mild stomach discomfort. Talk to a doctor before starting if you use blood thinners or blood pressure medication.