Grapefruit is a citrus fruit. Supplements use the peel, seeds, and fruit. These products carry a sharp safety warning. Grapefruit and its extracts, including seed extract, can powerfully alter liver metabolism of many prescription drugs. This change can raise or lower the potency of those medications to dangerous levels. Do not take grapefruit supplements if you use any prescription medication, especially statins, blood pressure drugs, antihistamines, or anxiety medications, without a doctor’s guidance.
The fruit supplies vitamin C and flavonoids like naringin and hesperidin. These compounds support antioxidant activity. Many people turn to grapefruit to help keep cholesterol levels and blood pressure in the normal range. Forms vary, from freeze-dried fruit capsules to liquid seed extract, so users follow the label for timing and amount.